Regenerative Salmon-DNA Injections

Imagine harnessing the power of DNA to repair and rejuvenate your skin – that’s exactly what Salmon-DNA injections aim to do. This treatment, also known in scientific terms as PDRN therapy (Polydeoxyribonucleotide), utilizes polynucleotides derived from salmon DNA to stimulate regeneration in the skin:contentReference[oaicite:22]{index=22}. It might sound a bit unusual, but extensive research has shown that these DNA fragments can have remarkable healing and anti-aging effects. Because salmon DNA is structurally similar to human DNA and highly biocompatible, our bodies accept it well. Once introduced into the skin, it kick-starts cell repair processes, encourages collagen production, improves elasticity, and deeply hydrates the tissue.

Regenerative Salmon-DNA injections are essentially a type of advanced skin booster. They don’t fill or paralyze anything; instead, they work at a cellular level. People who undergo this treatment often report that their skin becomes more radiant, fine lines are less noticeable, and there’s an overall improvement in tone and texture. It’s especially great for crepey or sun-damaged skin that needs a restorative boost, as well as for aiding recovery after aggressive procedures or helping with scars.

How the Treatment is Done

After cleansing the target areas (commonly the face and neck, though it can also be used on the hands or even stretch-marked areas), a topical anesthetic is usually applied to ensure you’re comfortable. The Salmon-DNA solution is then administered through a series of micro-injections into the dermis. We use a very fine needle and make numerous small injections across the skin – very similar to how traditional mesotherapy or skin booster treatments are done. Another method we sometimes use is to mix the Salmon-DNA with a small amount of local anesthetic and do slightly deeper injections, depending on the indication.

The process takes around 20-30 minutes. You will have lots of tiny bumps on your skin afterwards (where each droplet of the solution sits), and possibly some mild redness. These bumps are expected and will usually smooth out over the next day as the solution diffuses and is absorbed. There is minimal downtime; some people even do this over a long lunch break. If desired, we can also combine the injections with microneedling – applying some of the DNA topically and then using a microneedling device to help it penetrate (this can be an option for those who can’t tolerate many needle injections, or to enhance the effect on the surface). Regardless of method, we are essentially bathing your skin cells in a nutrient-rich, reparative broth.

Pre/Post Care

Preparation: Avoid blood thinners for a few days prior to minimize bruising risk, as with any injectable. Arrive with a clean face free of makeup. If you’ve recently had any laser or peel, let us know (though Salmon-DNA is often used after such treatments to speed healing, we would schedule appropriately). There’s no other special prep – ensure you’re not actively infected or having a breakout in the area, as we would wait for that to clear.

Aftercare: You’ll leave a bit red and bumpy. These tiny blebs of product will mostly settle within 24 hours. You can gently tap (don’t rub hard) the area if you want to help them along, but generally just leave them be. We advise no makeup until the next day, or at least for 6-8 hours if you must. Do not go into saunas, hot yoga classes, or engage in heavy exercise for 24 hours to reduce risk of swelling or bruising. Also avoid direct sun or tanning beds for a couple of days and wear SPF, since your skin might be a tad more sensitive right after. Some patients like to apply arnica cream to needle marks to help them fade. We will give you a soothing post-care cream to use that evening to calm the skin. Tiny bruises can occur at injection sites – they’re usually pinprick sized and fade quickly, but concealer can be used the next day if needed. Overall, downtime is very minimal; most people look fine by the next day, if not sooner.

Salmon-DNA injections are often done in a series of 2-4 sessions, spaced 2-4 weeks apart, for cumulative improvement. Then, maintenance treatments maybe twice a year can keep the skin benefits going. We’ll customize a plan based on your skin’s condition and your goals.

Frequently Asked Questions

What exactly is in Salmon-DNA injections and how does it work?
The key ingredient is PDRN (polydeoxyribonucleotide), which is basically fragments of DNA extracted from salmon sources. Don’t worry – it’s highly purified and safe. These DNA fragments have a remarkable ability to stimulate our skin’s repair mechanisms. They bind to specific receptors in our cells, promoting fibroblast activity (fibroblasts are the cells that produce collagen and elastin) and enhancing microcirculation. Essentially, PDRN tells the skin to regenerate: increase collagen, ramp up cell turnover, and improve tissue hydration. It also has anti-inflammatory properties:contentReference[oaicite:25]{index=25}, which is why it’s great for calming redness or aiding post-procedure healing. By improving the extracellular matrix (the environment around your skin cells), it makes the skin healthier and more resilient. Think of it as a powerful fertilizer for your skin’s garden, providing the nutrients and signals needed for growth and repair.

What skin issues can Salmon-DNA therapy help with?
It’s a versatile treatment. Primarily, it’s used for overall skin rejuvenation – improving texture, tone, and elasticity. So dull, rough, or sagging skin can see nice improvements. Fine lines and crinkles (like under-eye fine lines or smile line texture) can reduce as the skin plumps up with new collagen. It’s also excellent for hydration – if your skin is dry or lackluster, this gives it a deep moisturization from within. Additionally, it’s been used to help with acne scars or other scars, where inducing repair can gradually soften the scar tissue. Some practitioners use it for under-eye dark circles too, because it can improve circulation and thickness of the skin there, thus reducing the appearance of darkness. We’ll assess your particular concerns – for example, if someone has red, sensitive skin or post-acne inflammation, the anti-inflammatory effect can be beneficial. Even stretch marks have been treated with polynucleotide injections to improve their appearance. It’s not a one-stop cure for deep wrinkles or major sagging (that’s where fillers or lifting comes in), but as a part of a complete rejuvenation program, it addresses the quality of the skin itself, which is fundamental.

Is it safe? Any side effects to worry about?
Salmon-DNA or PDRN therapy is considered very safe. Since the active ingredients are naturally derived and similar to our body’s building blocks, the risk of allergic reaction is extremely low. The injection process carries the typical minor risks: pinpoint bleeding, small bruises, or transient redness. Infection is highly unlikely but theoretically possible whenever there are injections (we use antiseptic protocols to prevent this). One of the great aspects of this treatment is that it’s often used on people with sensitive skin or those who can’t tolerate other treatments, specifically because it reduces inflammation. So it’s gentle in that sense. After treatment, aside from looking a bit pink or bumpy for a short while, there aren’t really side effects. There’s no risk of filler-type complications or toxin spread, since this isn’t filling or freezing anything – it’s just boosting your skin’s own functions. Of course, pregnant or breastfeeding women should avoid elective injections as a precaution (even though it’s probably safe, it just hasn’t been studied in those groups). We’ll ensure you’re a good candidate health-wise before proceeding.

How is this different from PRP (Platelet-Rich Plasma)?
Great question – both Salmon-DNA (PDRN) and PRP are injectable regenerative treatments, and they’re somewhat similar in that they’re harnessing natural components to improve skin. PRP is drawn from your own blood and contains your platelets and growth factors which then stimulate repair. PDRN is an externally prepared product derived from salmon DNA that stimulates repair. PRP can be a bit more variable (since it depends on your blood sample quality and preparation) and its primary effect is growth factor release for a short period after injection. Salmon-DNA provides building blocks (nucleotides) and continuously triggers pathways in the skin over a longer period as it metabolizes. They actually complement each other well – some people even combine them, doing PRP and PDRN in alternating sessions or mixed together. PRP is great for overall rejuvenation too, but if someone cannot have blood drawn or wants a more standardized product, PDRN is a good option. PRP might be slightly better for things like stimulating hair growth or very specific healing scenarios, whereas PDRN might excel in direct skin quality improvements. We can discuss which is better for you, or whether a combination would yield maximum benefit.

How many sessions will I need and when will I see results?
While some people notice a “glow” and smoother feel to their skin within a week or two of the first session (once any injection marks heal), typically the improvements are cumulative. We often recommend a series of 3 sessions spaced about 2-4 weeks apart for initial therapy. Collagen production and skin turnover takes time – so about a month after your last session is when you’ll likely see the most noticeable results. Skin tends to be firmer, more even-toned, and just healthier-looking. Fine lines may be less apparent, and there’s often a slight “bounce” to previously crepey areas. If doing it for scar healing or post-laser recovery, you might notice those areas improving more rapidly than they would have on their own. After the initial series, depending on your skin goals, a maintenance session every 4-6 months can keep the effects going. Some of our patients do a single session in between other treatments as a pick-me-up for their skin. But for first-timers wanting a significant change, plan for multiple treatments. It’s a bit of delayed gratification, but because the change is gradual, it also looks very natural – like your skin just got better on its own (which, in truth, it did, with some help!).

Can I combine Salmon-DNA injections with other treatments?
Yes, and in fact, we encourage a holistic skincare approach. Salmon-DNA therapy pairs well with procedures like microneedling (as mentioned, sometimes we even administer it via microneedling), laser resurfacing (we might do PDRN injections a week after a laser to speed healing and boost results), or even with other injectables like PRF (Platelet-Rich Fibrin) or mesotherapy cocktails. It’s also a great add-on for people doing filler or toxin who also want that skin quality boost. We’d typically not do it on the exact same day as fillers or Botox to keep things straightforward, but you could do it in the same week or the week after. If you’re maintaining a routine with facials or chemical peels, those can be continued; we just might space them out (for example, do the peel two weeks before or after the injection). When creating your treatment plan, we’ll schedule things optimally. Salmon-DNA injections essentially prepare a healthy “soil” so that any “seeds” (other treatments) you plant will flourish better. Your skin will likely respond even better to other procedures when it’s in a nourished, regenerated state.